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Jan
Inotropic Effects On The Heart. Inotropic is a cardiac drug that affects cardiac contraction chronotropic is a cardiac drug that affects heart rate. Negative inotropes weaken the heart s contractions and slow the heart rate. Factors affecting the variation of angiotensin ii induced inotropic effects. These medicines are used to treat high blood pressure hypertension chronic heart failure abnormal heart rhythms arrhythmias and chest pain.
This medication is best for a patient with cardiomyopathy. For example enlarged heart muscle can increase inotropic state whereas de. Negative inotropes weaken the heart s contractions and slow the heart rate. An enlarged heart muscle can cause a positive effect due to the increased amount and strength of contraction. The most important mechanism regulating inotropy is the autonomic nerves. Sympathetic nerves play a prominent role in ventricular and atrial inotropic regulation while parasympathetic nerves vagal efferents have a significant negative inotropic effect in the atria but only a small effect in the ventricles.
The term inotropic state is most commonly used in reference to various drugs that affect the strength of contraction of heart muscle.
These medicines are used to treat high blood pressure hypertension chronic heart failure abnormal heart rhythms arrhythmias and chest pain. Types of the inotropic cardiac drug are the positive inotropic drug and the negative inotropic drug. However it can also refer to pathological conditions. For instance in the dog heart glucagon produces a robust inotropic effect in ventricular myocardium 9 but only a slight contractile effect in atrial myocardium 10. An inotrope help 1 is an agent that alters the force or energy of muscular contractions. Mi can cause dead heart tissue which causes a negative effect.